Bruno scored in the 30th minute through a Pogba pass to give United the lead. United maintained the lead in the first half. But early in the second half, Leeds equalized. Leeds' Luca Ayling equalized in the 48th minute.
After that, United put pressure on the game and scored three goals in 10 minutes. Greenwood scored in the 52nd minute and Bruno in the 54th minute to give United a 3-1 lead. Pogba assisted for both goals.
In the 60th minute, Bruno completed the hat trick by scoring on a pass from Victor Lindloff.
Then in the 68th minute, Fred scored the fifth goal for United in Pogba's pass. Pogba became the seventh player and the first United player to have four assists in a single Premier League game. He had only three assists in 26 games last season.
Jadon Sancho also made his debut for United through this game. He replaced Daniel James in the second half.